New Cochrane Protocols February 2013
There are three new protocols on the February issue of the Cochrane Library The first protocol Carrasco-Labra A, Brignardello-Petersen R, Yanine N, Araya I, Rada G, Chadwick RG. Professionally-applied...
View ArticleOral cancer support needs are highly subjective and varied in severity across...
Worldwide oral and oropharyngeal cancer is the 6th most common cancer. Treatment often affects the individuals’ ability to eat, speak and interact with others and so is associated with significant...
View ArticleOral examination to detect potentially malignant disorders and mouth cancer
November is Mouth Cancer Awareness month here in the UK and around 6,500 cases are diagnosed a year. Mouth cancer is the 6th commonest cancer worldwide. In India, Sir Lanka and Pakistan it is the most...
View ArticleLimited evidence to decide whether visual screening reduces the death rate...
Yesterday we looked at a review of the effectiveness of oral examination to detect potentially malignant disorders and mouth cancer today we are looking the latest version of the Cochrane review on...
View ArticlePositive association between alcohol drinking and upper aerodigestive tract...
Mouth cancers form part of a wider group of upper aerodigestive tract (UADT) cancers (oral cavity, pharynx, larynx, and oesphagus), which are strongly associated with smoking and alcohol. The aim of...
View ArticleOral cancer detection: Limited evidence for use of chemiluminescence and...
Early detection of oral cancer improves prognosis so methods to improve diagnosis are welcome. The review we look at today looks at two light-based systems: chemiluminescence or autofluorescence. 25...
View ArticleAlcohol consumption increased oral cancer risk
This new review investigated the effect of alcohol on 23 cancer types. They included 572 case-control and cohort studies and using meta-analysis and a dose–response meta-regression model found relative...
View ArticlePhotodynamic therapy: review finds insufficient evidence of its effectiveness...
This review of photodynamic therapy (PDT) for oral premalignant lesions only identified a small number of poor quality studies that provide insufficient evidence for the effectiveness of PDT for the...
View ArticleOral Cancer diagnosis: biopsy and histology still best method
This Cochrane review of adjunctive diagnostic tests for oral cancer included 41 studies assessing vital staining, cytology, and light-based tests. The available studies were of poor quality detection...
View ArticleOral leukoplakia: malignant transformation rate highly variable
This review of the malignant transformation rate of oral leukoplakia included 24 studies, the majority of which were retrospective. The range of malignant transformation was between 0.13% and 34.0%....
View ArticleOral Cancer – DNA-image cytometry may have promise for early detection
This diagnostic review compared two computer aided adjunctive tests for oral cancer. Oral CDX and DNA-image cytometry. The results suggest that DNA-image cytometry has a highly significant potential...
View ArticleSmokeless tobacco – do behavioural and pharmacological interventions help...
Dominic Hurst looks at the recent Cochrane review of interventions to help smokeless tobacco (ST) users quit. ST use is linked to oral cancer, precancer and periodontal disease, so dentists have an...
View ArticleOral cancer- monoclonal antibodies combined with standard treatment may...
12 trials were included in this Cochrane review of molecularly targeted therapies and immunotherapies as adjuncts to standard treatments for oral cancer. Moderate evidence was found that standard...
View ArticleTobacco use and alcohol intake key risk factors for head and neck cancer
The International Head and Neck Cancer Epidemiology (INHANCE) consortium is a collaboration of research groups leading large epidemiology studies to improve the understanding of the causes and...
View ArticleCoffee consumption and oral cancer
This review includes 11 case-controlled and 4 cohort studies and suggests a 37% reduction of oral cancer risk in high coffee drinkers compared with low or no coffee drinkers OR= 0.63 (95%CI; 0.52 -...
View ArticleHigh frequency or prolonged use of mouthwash increased risk of head and neck...
This study from the INHANCE collaboration pooled data from 12 case-controlled studies. Long-term use (35 yrs) of mouthwash was associated with an increase risk OR=1.15 (95%CI; 1.01 to 1.30) of head and...
View ArticleMarijuana use and head and neck cancer risk #CannabisMatters
9 case-controlled studies were included in this review of the effect of marijuana use on head and neck cancer. The findings suggest no association marijuana use and head and neck cancer but other...
View ArticleOral Mucositis: can honey reduce its severity?
This review of the use of honey to educe the severity of radio/chemotherapy-induced oral mucositis identified 7 low quality RCTs that suggest that use of honey may reduce the severity of oral...
View ArticleTop Dental Elf Blogs of 2016
During 2016 the Dental Elves has published 158 blogs covering a broad range of topics. The most popular blogs of each month are highlighted. The post Top Dental Elf Blogs of 2016 appeared first on...
View ArticleOral mucositis in cancer patients: no benefit from chlorhexidine mouthwash
This review of chlorhexidine (CHX) for prevention & treatment of oral mucositis included 12 RCTs with 9 contribution to the meta-analysis. CHX was not significantly effective in preventing...
View Article