Sexual behaviours and oral cancer risk
20 studies reporting 21 data sets were included in this review of the association of sexual behaviours and oral and oropharyngeal cancers. The review suggests that some sexual behaviours increase risk...
View ArticlePotentially malignant disorders of the oral cavity: Evaluation guideline
This new clinical practice guideline from the American Dental Association (ADA) updates the 2010 guideline on “Evidence-based Clinical Recommendations Regarding Screening for Oral Squamous Cell...
View ArticleOral potentially malignant disorders – how common are they?
This review of the prevalence of oral potentially malignant disorders included 22 observational studies providing a pooled estimate for prevalence of 4.47% (95% CI;2.43-7.08). The post Oral potentially...
View ArticleOral lichen planus: Rate of malignant transformation
This review of the malignant transformation rate (TR) of oral lichen planus included 21 observational studies the majority of which were retrospective. The overall estimate of TR was 1.4%. The post...
View ArticleMouth and throat cancer: evidence for best surgical approaches uncertain
12 RCTs were included in this Cochrane review update of surgical approches for the management of oral and pharyngeal cancer. The certaintly of the evidence was very low as there were limited numbers of...
View ArticleOral Cancer: Elective or therapeutic neck dissection?
This review of neck dissection (END) in patients with squamous cell carcinoma (SCC) of the oral cavity and clinically N0 neck included 6 studies suggesting fewer recurrences with END, but the evidence...
View ArticleDental visits and head and neck cancer
This review of a link between past dental visits/check-ups and the incidence cancers of head and neck includes 38 studies the majority of which are case-controlled studies. The findings suggest that...
View ArticleCoffee and oral cavity cancer risk
This review of the association between coffee intake and the risk of oral cancer includes 19 studies and suggestes that higher intak may be linked with a reduced risk of oral cancer. The post Coffee...
View ArticleOral mucositis in cancer patients: the effect of oral supplementation
This review of of the effects of oral supplementation on the prevention and/or treatment of oral mucositis in patients with cancer undergoing chemotherapy and/or radiotherapy included 12 RCTs and...
View ArticleOral Cancer: Elective neck dissection or watch and wait?
There is an ongoing debate about the management of patients with oral cavity squamous cell carcinoma and clinically negative cervical lymph nodes. Some clinicians favour preventive elective neck...
View ArticleToombak: A risk factor for oral leukoplakia and cancer
This review of the association between toombak use and oral leukoplakia and oral squamous cell carcinoma included 8 observational studies suggesting a strong association. The post Toombak: A risk...
View ArticleElective neck dissection for early stage oral cancer?
This UK multi-centre RCT of elective neck dissection(END) for early stage oral cancer found higher rates for overall and disease free survival in those patients having END. The post Elective neck...
View ArticleOral lichen planus: malignant transformation rate
This review of the malignant transformation rate of oral lichen planus and associated risk factors included 33 studies. Using a strict definition the authors found a malignant transformation rate of...
View ArticleElective neck dissection versus observation for T1-2 oral squamous cell...
Manas Dave looks at a review of elective neck dissection (END) versus observation for the management of T1-2 oral squamous cell carcinoma. The review included 41 studies only 5 were RCTs the remainder...
View ArticleOral Cancer – Referral by primary care doctors and dentists
This review comparing primary care doctors and dentists in the referral of oral cancer included 22 mainly retrospective studies. Doctors refered sliightly more than dentists, typically 50% compared...
View ArticleOptical fluorescence imaging in oral cancer and potentially malignant disorders
Manas Dave looks at a recent review of which considers the efficacy of optical fluorescence imaging as an adjunct to clinical oral examination for the detection of oral mucosal lesions. The review...
View ArticleSalivary biomarkers CYFRA 21-1 and MMP-9 for oral squamous cell carcinoma...
In his first blog for the Dental Elf Rajpal Tattar take a look at a review of the diagnostic accuracy of salivary biomarkers for the detection of oral squamous cell carcinoma (OSCC). The review...
View ArticleBetel quid and areca nut chewing and oral cancer prognosis
This review of the links between the habit of betel quid and areca nut (BQ-AN) chewing and the prognosis of oral cancer included 11 observational studies. The findings suggest that lower 5-year...
View ArticleOsteoradionecrosis incidence and the timing of dental extractions
This review of whether the incidence of osteoradionecrosis differed between patients who have dental extractions before or after radiotherapy (RT) included 24 studies (19 retrospective 5 prospective)....
View ArticleMicroRNAs for diagnosis of squamous cell carcinoma
Manas Dave looks at a review of the diagnostic accuracy of blood and salivary microRNAs (miRNAs) in discriminating oral squamous cell carcinoma. The review included 20 cross-sectional studies and...
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